The GUESS Unified Editing Suite & SDK is open-source, licensed under the GNU GPL v.2.0.
Open source can cure cancer. Not just one type of cancer. All types. Open source can rid us of autoimmune disorders which can range from irritating to fatal. Open source can give us all a democratic, equal platform on which to design ourselves, define our biological futures, gain the upper hand in the arms race with viruses and bacteria, and adapt to new realities.
It is not a matter of if, but of when and by whom. Our effort will not stand alone. But it will stand for the many rather than the few.
We develop software best together. Let's change the world by being the change, one carefully simulated and debugged gene edit at a time.
Here are the 25 modules plus our Yeast based MVP project arranged alphabetically, each has a link to its Taiga project management page and the Gitlab page on our servers, you are encouraged to make your own git forks, copies and backups.
Bioelectric Effects is a #Neuroscientific module which will model the effects of bioelectric disturbances on other cells and allow the development of insulative layers and other solutions or exploits of such effects. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Bioelectric_Effects and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-bioelectric-effects/kanban
DEFS is a #VictoryVectors module for the assembly of and safe propagation and implementation of Vectors and their contents. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/DEFS and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-defs/kanban
DIBS is Database Integration Built Securely. This is a module of the GUESS itself, it acts to bind together the rest of the modules with various bioinformatics databases to increase efficiency through sharing resources. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/DIBS and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-dibs/kanban
DNA Computing: This is a #VulpineComputing and #VictoryVectors crossover module for the exploration of DNA-based computing and storage technologies and their direct implementation potential in a Victory Vectors setting. Gitlab: No repo yet available, we're working on a few matters of protective common sense before we open this one to the public. and Taiga: Likewise, the project management page for this one is pending a few outstanding issues being resolved. Be patient, a couple of years does not mean forgotten.
Electrical Signalling is a #Neuroscientific module which may also be deployed in non-neuronal cellular simulations, e.g. the development of bio-electronics. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Electrical_Signalling and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-electrical_signalling/kanban
Epigenetic Mothballing: This #VictoryVectors module of The GUESS will allow the creation of backups of genetic information or the deactivation of tranches of genetic information through the use of epigenetic tags and packing. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Epigenetic_Mothballing and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-epigenetic-mothballing/kanban
GeFi (Genetic Fidelity) is the front-end of The GUESS's #GraphicalModel modules. This is the interface through which edits to the model of the body will be done, in order to test and construct 'molecures' for the real thing. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/GeFi and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-gefi/kanban
Geneticiser Driver is a module for the fine tuned controls and software to hardware interfacing of the Geneticiser. This is a #HardwareDrivers & #Firmware module. Gitlab: No repo yet available, we're working on a few matters of protective common sense before we open this one to the public. and Taiga: Likewise, the project management page for this one is pending a few outstanding issues being resolved. Be patient, a couple of years does not mean forgotten.
HIP_DAME (Hormones, Immunity & Pathways, Dismantlement & Apoptosis Models of Effects): #GeneralCellular modules of the GUESS, handling a broad range of effects on multiple levels from hormones and protein pathways via immunity to cell death and recycling. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/HIP_DAME and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-hip_dame/kanban
INITIATOR_SET Now Identified Through Informatics of Alternative Translational Organisation of RNAs & Sequence Editing Techniques (the name is a recursive acronym reminiscent of scientific paper titles). This is a #GeneralCellular Module of The GUESS. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/INITIATOR_SET and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-initiator-set/kanban
Laberation: Liberation from aberration, through collaberation in Laberation! This is the online sharing lab & store that provides our platform for the world to share their gene edits and cures. Somewhere between Gitlab, Bandcamp, Openbazaar and Crypto-Swartz. Think Distrowatch.com but for genes and using a blockchain, decentralised and with a purchase system built in. Gitlab: https://gitlab.vulpinedesigns.co.uk/danfox/Laberation and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-laberation/kanban
LERM: Lipid Effects & Rafts Modelling. This is a #GeneralCellular Module of the GUESS. It is focussed on working out the roles of lipids and their aggregated forms in cellular processes when fed specific parameters. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/LERM and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-lerm/kanban
Microbiome: This is for anything specific to the microbiome; the gut bacteria, the organisms on your skin and in your various crevices and orifices. It is the module for ensuring they are not negatively affected by genetic modifications or mutations. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Microbiome and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-microbiome/kanban
Neng: Nanotechnological Engineering. This #VictoryVectors module handles the creation of properly synthetic devices made for use with, by or as all or part of the Vectors. Includes the ROVERS vector system. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Neng and Taiga: https://taiga.vulpinedesigns.co.uk/project/quokkaneer-neng/kanban
Nerve Growth: The growth of nerves is so different, it gets its own #Neuroscientific module for The GUESS. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Nerve_Growth and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-nerve-growth/kanban
Nutricator: Nutricator is a module for the calculation of the nutritional requirements of the application of a genetic modification vector or other treatment to the body. This includes energy, minerals, basic biological molecules & non-natively sourced vitamins. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Nutricator and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-nutricator/kanban
OGRE, The: The Optical Genetic Recognition Engine. This is a system that can be used as a GUESS module or separately, to interpret the scanning inputs and to smartly direct scanning apparatus of the Geneticiser for optimal DNA reading from optical imagery. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/The_OGRE and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-the-ogre/kanban
PAMM: Prion & Amyloid Mitigation & Management. This is a #GeneralCellular module, focused on protein folding and interactions. Its components include a Denaturing Mitigation and Management analysis tool, access to protein fold rules and databases. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/PAMM and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-pamm/kanban
SLoMSO: Strain & Load Modelling & Structural Optimisation. This is a #GraphicalModel Module for the GUESS. It requires the use of physics and graphics processing. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/SLoMSO and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-slomso/kanban
TentPoles: Cytoskeletal modelling modules, linkable to structural models on other scales/levels and including allowance for the inclusion of Quantum Cytoskeletal Effects Amplification Modelling when technology allows. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/TentPoles and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-tentpoles/kanban
Transcription: This #GeneralCellular Module of the GUESS includes Transcription Factor Determination and will eventually, once technology allows, include Quantum Nucleoacoustics modelling. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Transcription and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-transcription/kanban
Uncanny Valley: This is a visual recognition AI sense-checking algorithm intended to supplement the range of warnings and errors The GUESS can provide with regard to cosmetic effects of changes, during simulation. It is a #GraphicalModel Module of The GUESS. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Uncanny_Valley and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-uncanny-valley/kanban
Vectors Factors: The Transcription Factors needed for the propagation and implementation of a Vector are calculated in this #VictoryVectors variant on the General Cellular 'Transcription' module. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Vectors_Factors and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-vectors_factors/kanban
Vectron: The purpose of Vectron is to switch the vectors on and to transmit data securely to them. This is a Hardware Drivers & #Firmware module for The GUESS. Gitlab: https://gitlab.vulpinedesigns.co.uk/TheGUESSUniversalEditingSuiteandSDK/Vectron and Taiga: the project management page for this one is pending a few outstanding issues being resolved. Be patient, a couple of years does not mean forgotten.
Yeast Artificial Chromosomes and/or CRISPR editing of Yeast, to alter Yeast so that it expresses the Major Histocompatibility Complex and associated pathways necessary to display protein fragments on the surface. This allows the wet-lab testing of autoimmune disorders using yeast modified to express human proteins and human immune cells. This is not strictly a module of the GUESS, but it can act as a catalyst for their development. It is classified as a sub-project of HIP_DAME. Gitlab: see HIP_DAME. and Taiga: https://taiga.vulpinedesigns.co.uk/project/danfox-hip_dame/us/1?kanban-status=33
The more astute among you will notice that's only 24 modules plus the Yeast CRISPR Templates. The other one is a little Easter Egg thing for fun we'll keep under wraps for now. :-)